Determination of the milk pharmacokinetics and depletion of milk residues following intramammary administration of cephapirin sodium in lactating dairy goats
In the United States, between 2007 and 2017, the US Department of Agriculture’s National Agricultural Statistics Service reported dairy operations that had milk goats to be the fastest growing operations in the nation. The most impactful and economically important health challenge to dairy goat herds is mastitis. Currently, there are no labelled products for the treatment of mastitis in dairy goats and minimal research has been conducted to evaluate the pharmacokinetics of intramammary-administered antimicrobials. The objectives of this study were to determine the pharmacokinetics in milk of dairy goats treated with intramammary (IMM) cephapirin sodium and determine an appropriate withdrawal time for milk.